Posts Tagged ‘tumor cells’

Biologists unravel drug-resistance mechanism in tumor cells

Wednesday, December 14th, 2016
Biologists unravel drug-resistance mechanism in tumor cells

Targeting the RNA-binding protein that promotes resistance could lead to better cancer therapies.

Anne Trafton | MIT News Office
October 22, 2015

  • P53, which helps healthy cells prevent genetic mutations, is missing from about half of all tumors. Researchers have found that a backup system takes over when p53 is disabled and encourages cancer cells to continue dividing. In the background of this illustration are crystal structures of p53 DNA-binding domains.

    P53, which helps healthy cells prevent genetic mutations, is missing from about half of all tumors. Researchers have found that a backup system takes over when p53 is disabled and encourages cancer cells to continue dividing. In the background of this illustration are crystal structures of p53 DNA-binding domains.

    Image: Jose-Luis Olivares/MIT (p53 illustration by Richard Wheeler/Wikimedia Commons)

How cancer cells fuel their growth

Wednesday, March 16th, 2016

Scientists surprised to find amino acids, not sugar, supply most building blocks for tumor cells.

Scientists had believed that most of the cell mass that makes up new cells, including cancer cells, comes from that glucose. However, MIT biologists have now found, to their surprise, that the largest source for new cell material is amino acids, which cells consume in much smaller quantities.

Anne Trafton | MIT News Office
March 7, 2016

http://news.mit.edu/2016/how-cancer-cells-fuel-their-growth-0307